Serum Ratios of Triiodothyronine to Thyroxine and Reverse-triiodothyronine in Graves' Disease and Destruction-induced Thyrotoxicosis

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[Serum ratios of triiodothyronine to thyroxine and reverse-triiodothyronine in Graves' disease and destruction-induced thyrotoxicosis].

In order to determine the frequency of thyroxine (T4) toxicosis and study the possibility of usefulness for differentiation between thyrotoxic Graves' disease and destructioninduced thyrotoxicosis, the serum concentrations of T4, triiodothyronine(T3), reverse T3 (rT3), and T4-binding globulin (TBG) and the values of T3-uptake and radioactive iodine uptake (RAIU) were measured, and free, T4 inde...

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Ratio of serum free triiodothyronine to free thyroxine in Graves' hyperthyroidism and thyrotoxicosis caused by painless thyroiditis.

The serum T3 to T4 ratio is a useful indicator for differentiating destruction-induced thyrotoxicosis from Graves' thyrotoxicosis. However, the usefulness of the serum free T3 (FT3) to free T4 (FT4) ratio is controversial. We therefore systematically evaluated the usefulness of this ratio, based on measurements made using two widely available commercial kits in two hospitals. Eighty-two untreat...

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Peripheral serum thyroxine, triiodothyronine and reverse triiodothyronine kinetics in the low thyroxine state of acute nonthyroidal illnesses. A noncompartmental analysis.

The low thyroxine (T(4)) state of acute critical nonthyroidal illnesses is characterized by marked decreases in serum total T(4) and triiodothyronine (T(3)) with elevated reverse T(3) (rT(3)) values. To better define the mechanisms responsible for these alterations, serum kinetic disappearance studies of labeled T(4), T(3), or rT(3) were determined in 16 patients with the low T(4) state and com...

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Differentiating Graves' disease from subacute thyroiditis using ratio of serum free triiodothyronine to free thyroxine

BACKGROUND The measurement of free thyroid hormone, instead of the total form, is more commonly used in current practice. We aimed to evaluate the usefulness of the ratio of serum free triiodothyronine (FT3, pg/mL) to free thyroxine (FT4, ng/dL) for differentiating Graves' disease from subacute thyroiditis. MATERIALS AND METHODS Medical records of thyrotoxic patients aged >15 years who had me...

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Presence of triiodothyronine, no detectable thyroxine and reverse triiodothyronine in human milk.

Thyroxine (T4), triiodothyronine (T3) and reverse triodothyronine (rT3) concentrations in human milk were measured by radioimmunoassay in 114 samples obtained from 1 week to 8 months postpartum. Several assay systems applied for the determination of serum thyroid hormone concentration were proved to be unsuitable for human milk, and the method of separating free and antibody-bound hormone by po...

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ژورنال

عنوان ژورنال: Folia Endocrinologica Japonica

سال: 1983

ISSN: 0029-0661

DOI: 10.1507/endocrine1927.59.1_81